Acta Neuropathologica Communications September 2013

This book contains open access research articles from September of 2013 published in Acta Neuropathologica Communications. Topics include: The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease; Glial scaffold required for cerebellar granule cell migration is dependent on dystroglycan function as a receptor for basement membrane proteins; Decreased neuroinflammation and increased brain energy homeostasis following environmental enrichment after mild traumatic brain injury is associated with improvement in cognitive function; N-truncated Abeta starting with position four: early intraneuronal accumulation and rescue of toxicity using NT4X-167, a novel monoclonal antibody; Excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol; The Arctic AbetaPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Abeta; The link between intraneuronal N-truncated amyloid-beta peptide and oxidatively modified lipids in idiopathic autism and dup(15q11.2-q13)/autism; The airbag problem-a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer's disease.