Application For Nanotechnology For The Treatment Of Brain Diseases And Disorders

Brain diseases and disorders, such as dementia and glioblastoma, are among the deadliest diseases in humans, and put an overwhelming burden on healthcare systems. Despite recent progress in elucidating the causes of brain diseases, a limited amount of effective therapeutics have been developed. One major obstacle is the efficient delivery of therapeutic agents across the Blood-Brain Barrier (BBB) into the affected region of the brain. Utilizing nanoparticles as a drug delivery system provides a simple and effective approach, with improved efficacy and bioavailability. In the last two decades, numerous advances have been made in this field, which will bring nanomedicine closer to the clinic and bring new therapeutic options for the treatment of brain diseases which have proved challenging to treat. Such advancements include improvements in the novel design of nanoparticles with tissue compatibility, versatile loading capacity, BBB penetration ability and greater target specificity.