Case Studies In Immunology Interleukin 1 Receptor Associated Kinase 4 Deficiency
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Case Studies in Immunology: Interleukin 1 Receptor-associated Kinase 4 Deficiency
Author | : Raif Geha |
Publisher | : Garland Science |
Total Pages | : 15 |
Release | : 2010-01-01 |
Genre | : Medical |
ISBN | : 1136984666 |
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This case study is about a 6-year-old boy with recurrent pneumococcal meningitis. It provides information on an inability of the innate immune system to detect pathogen presence, and the sequencing of DNA for the IRAK4 gene that revealed a homozygous nonsense mutation within the kinase domain.