Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis
Author: Rupinder K. Sodhi
Publisher: Academic Press
Total Pages: 432
Release: 2020-10-15
Genre: Medical
ISBN: 0128157631

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Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research. Offers standard and innovative therapeutic approaches to modulate apoptosis in clinical interventions, such as cardiovascular diseases, immune disorders, cancer chemotherapy and neurological ailments Covers cutting-edge laboratory techniques and traditional protocols to determine apoptosis, both in vitro and in vivo Examines clinical study reports of new drug moieties that are explored for various pathological conditions associated with apoptosis


Clinical Perspectives and Targeted Therapies in Apoptosis
Language: en
Pages: 432
Authors: Rupinder K. Sodhi
Categories: Medical
Type: BOOK - Published: 2020-10-15 - Publisher: Academic Press

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Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cel
Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
Language: en
Pages: 411
Authors: Marek Los
Categories: Medical
Type: BOOK - Published: 2006-06-20 - Publisher: Springer Science & Business Media

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As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
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Pages: 260
Authors: Christopher D. Gregory
Categories: Medical
Type: BOOK - Published: 2016-08-24 - Publisher: Springer

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This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-t
Apoptosis
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Categories: Medical
Type: BOOK - Published: 2010-07-19 - Publisher: CRC Press

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Targeting the key active elements in the mechanism and application of apoptosis and its therapeutic implications, Apoptosis: Modern Insights into Disease from M
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Language: en
Pages: 211
Authors: Daniel Gioeli
Categories: Medical
Type: BOOK - Published: 2011-06-02 - Publisher: Springer Science & Business Media

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This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resi