Dose Optimization in Drug Development

Dose Optimization in Drug Development
Author: Rajesh Krishna
Publisher: CRC Press
Total Pages: 328
Release: 2006-05
Genre: Medical
ISBN:

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This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD, this volume critically highlights the multidisciplinary nature of drug development and spans the fields of pharmacokinetics, clinical pharmacology, biostatistics, and experimental medicine.


Dose Optimization in Drug Development
Language: en
Pages: 328
Authors: Rajesh Krishna
Categories: Medical
Type: BOOK - Published: 2006-05 - Publisher: CRC Press

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This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug
Improving and Accelerating Therapeutic Development for Nervous System Disorders
Language: en
Pages: 107
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 2014-02-06 - Publisher: National Academies Press

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Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervo
Early Drug Development
Language: en
Pages: 507
Authors: Mitchell N. Cayen
Categories: Medical
Type: BOOK - Published: 2011-02-25 - Publisher: John Wiley & Sons

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The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategie
The Drug Development Paradigm in Oncology
Language: en
Pages: 145
Authors: National Academies of Sciences, Engineering, and Medicine
Categories: Medical
Type: BOOK - Published: 2018-02-12 - Publisher: National Academies Press

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Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system r
Novel Designs of Early Phase Trials for Cancer Therapeutics
Language: en
Pages: 0
Authors: Shivaani Kummar
Categories: Medical
Type: BOOK - Published: 2018-05-26 - Publisher: Academic Press

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Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the inte