Engineering Microbes For Therapy

Microbes can play protective role in human health, and the concepts of probiotics and microbiota have been well established in recent years. Probiotics have an important economic impact in food, food supplement and veterinary industry with increasing market size. Engineering microbes for therapy can lead to selection of new microbial strains and mixtures, or targeted improvement of existing microbial strains, achieved by mutagenesis, genetic engineering and synthetic biology. Engineering of microbes can also encompass the development and improvement of their dosage forms. Possible uses of engineered microbes include antigen delivery, immunomodulation, inflammation, cancer, infectious diseases and metabolic disorders. The eBook represents an up-to-date overview, shows new results, as well as demonstrates future trends in the developing field of therapeutic microbial engineering.