Identification Of Biomarkers For Cancer Immunotherapy From Bench To Bedside Volume I
Download Identification Of Biomarkers For Cancer Immunotherapy From Bench To Bedside Volume I full books in PDF, epub, and Kindle. Read online free Identification Of Biomarkers For Cancer Immunotherapy From Bench To Bedside Volume I ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Identification of Biomarkers for Cancer Immunotherapy: From Bench to Bedside, volume I
Author | : Chang Gu |
Publisher | : Frontiers Media SA |
Total Pages | : 191 |
Release | : 2023-10-20 |
Genre | : Science |
ISBN | : 2832529275 |
Download Identification of Biomarkers for Cancer Immunotherapy: From Bench to Bedside, volume I Book in PDF, Epub and Kindle
During the past few decades, immunotherapy has become an established pillar of cancer treatment improving the survival of numerous patients with diverse solid and hematologic tumors. The leading causes behind the success are the discovery of immune checkpoint inhibitors (ICIs) and the development of chimeric antigen receptor (CAR) T/M/NK cells. As for ICIs, malignancies take advantage of the inhibitory programmed cell death protein 1/programmed cell death protein ligand 1 (PD-1/PD-L1) or cytotoxic T-lymphocyte-associated protein (CTLA-4) pathways to evade the immune system, and disruption of the axis by immune checkpoint inhibitors can achieve durable disease remissions, which has been proved by basic researches and (pre-) clinical studies among lung cancer, melanoma, renal cell cancer, head, and neck squamous cell carcinoma, urothelial cancer, and Hodgkin’s disease. However, the 5-year survival rate of patients treated with ICIs varies with each individual and also relies on tumor specific pathological or molecular subtypes. Besides, the efficacy of ICIs is still limited in terms of drug resistance and fewer potential responders. Thus, there is a big challenge to identify and develop more novel reliable ICIs, as well as sensibilize existing ICIs for patients with drug resistance or even for non-responders.
Identification of Biomarkers for Cancer Immunotherapy: From Bench to Bedside, volume I Related Books
Pages: 191
Pages:
Pages: 338
Pages: 0
Pages: 406