Integrated Cardiac Safety
Language: en
Pages: 500
Authors: J. Rick Turner
Categories: Medical
Type: BOOK - Published: 2008-11-26 - Publisher: John Wiley & Sons

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The serious nature of cardiovascular adverse drug reactions occurring in patients makes assessment of a drug's cardiac safety profile a high priority during bot
Cardiovascular Safety in Drug Development and Therapeutic Use
Language: en
Pages: 342
Authors: J. Rick Turner
Categories: Medical
Type: BOOK - Published: 2016-07-28 - Publisher: Springer

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At a time when the field of cardiac safety is going through important changes, this unique book provides the rationale for, and cutting-edge explanations of, ne
Predictive ADMET
Language: en
Pages: 604
Authors: Jianling Wang
Categories: Medical
Type: BOOK - Published: 2014-02-28 - Publisher: John Wiley & Sons

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This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokineti
Pharmaceutical Competitive Intelligence for the Regulatory Affairs Professional
Language: en
Pages: 94
Authors: Raymond A. Huml
Categories: Medical
Type: BOOK - Published: 2012-06-15 - Publisher: Springer Science & Business Media

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This Brief defines competitive intelligence (CI) as a tool for making investment decisions within the pharmaceutical industry. It provides an overview of proces
Integrative Computational Modeling of Calcium Handling and Cardiac Arrhythmias
Language: en
Pages: 350
Authors: Henry Sutanto
Categories: Medical
Type: BOOK - Published: 2021-01-01 - Publisher: Henry Sutanto

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Cardiomyocyte calcium handling is a major determinant of excitation-contraction coupling. Alterations in one or more calcium-handling proteins may induce arrhyt