Outstanding Features Of Recent Advances In Cochlear Gene Therapy
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“Outstanding Features of Recent advances in Cochlear Gene Therapy.”
Author | : DR. HAKIM. SABOOWALA |
Publisher | : Dr.Hakim Saboowala |
Total Pages | : 35 |
Release | : 2019-11-12 |
Genre | : Medical |
ISBN | : |
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Cochlear gene therapy has undergone tremendous advances over the past decade. Beginning with some groundbreaking work in 2005 documenting hair cell regeneration using virally mediated delivery of the mouse atonal 1 gene, gene therapy is now being explored as a possible treatment for a variety of causes of hearing loss. Recent advances in cochlear gene therapy include improved methods of gene delivery with a better delineation of viral vectors that are suitable for this purpose, additional improvements in hair cell regeneration, and directed research towards: · Autoimmune hearing loss, · Ototoxicity, · Spiral ganglion survival, and · Genetic forms of hearing loss. If successful, cochlear gene therapy will dramatically alter our ability to treat a variety of forms of acquired and genetic hearing loss. An attempt has been made in this Booklet to highlight recent advances in cochlear gene therapy over the past several years. ….. Dr. H.K.Saboowala.M.B.(Bom) M.R.S.H.(London)
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