PARP as a Therapeutic Target

PARP as a Therapeutic Target
Author: Jei Zhang
Publisher: CRC Press
Total Pages: 363
Release: 2002-03-06
Genre: Medical
ISBN: 1420042408
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Recent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the details of how PARP1 functions are still being elucidated, it has tremendous potential as a promising drug target. PARP inhibitors' dual actions of preventing cell death and abating inflammati