Principles Of Process Research And Chemical Development In The Pharmaceutical Industry
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Principles of Process Research and Chemical Development in the Pharmaceutical Industry
Author | : Oljan Repic |
Publisher | : Wiley-Interscience |
Total Pages | : 248 |
Release | : 1998 |
Genre | : Medical |
ISBN | : |
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This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.
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