Proteostasis and Disease

Proteostasis and Disease
Author: Rosa Barrio
Publisher: Springer Nature
Total Pages: 350
Release: 2020-04-09
Genre: Science
ISBN: 3030382664

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This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology. Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.


Proteostasis and Disease
Language: en
Pages: 350
Authors: Rosa Barrio
Categories: Science
Type: BOOK - Published: 2020-04-09 - Publisher: Springer Nature

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This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and di
Proteostasis and Proteolysis
Language: en
Pages: 277
Authors: Niki Chondrogianni
Categories: Science
Type: BOOK - Published: 2021-11-30 - Publisher: CRC Press

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Proteostasis integrates biological pathways controlling biogenesis, trafficking, folding, and degradation of proteins. This book focuses on two protein breakdow
Proteostasis and Chaperone Surveillance
Language: en
Pages: 184
Authors: Laishram Rajendrakumar Singh
Categories: Science
Type: BOOK - Published: 2015-11-26 - Publisher: Springer

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Proteostasis is central to the development of various human diseases caused due to excessive protein misfolding and the disregulation of the protein quality con
Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches
Language: en
Pages: 265
Authors: Claudia Duran-Aniotz
Categories: Science
Type: BOOK - Published: 2022-10-05 - Publisher: Frontiers Media SA

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HSF1 and Molecular Chaperones in Biology and Cancer
Language: en
Pages: 185
Authors: Marc Laurence Mendillo
Categories: Medical
Type: BOOK - Published: 2020-04-15 - Publisher: Springer Nature

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Protein homeostasis, or “Proteostasis”, lies at the heart of human health and disease. From the folding of single polypeptide chains into functional protein