Pulmonary Actions of the Endothelins

Pulmonary Actions of the Endothelins
Author: Goldie
Publisher: Springer
Total Pages: 292
Release: 2012-12-06
Genre: Medical
ISBN: 303488821X

Download Pulmonary Actions of the Endothelins Book in PDF, Epub and Kindle

The biology of the family of endogenous autocrine peptides known as the endothelins (ETs) has been a source of intense study for researchers since 1988, following the identification of ET-l as the previously described endothelium-derived contractile factor. Initial interest focussed on the actions of the ETs in the cardiovascular system, and this remains the pri mary source of published work involving these peptides. Importantly, evi dence is mounting for a significant mediator role for ET-l in cardiovascu lar diseases including systemic hypertension and congestive heart failure. However, it was also recognized early on that the ETs exert an array of powerful actions in the respiratory tract, many of which prompted specula tion concerning mediator roles for ET-l in several lung diseases including asthma and pulmonary hypertension. In recent years the evidence for the involvement of ET-l in lung diseases has become more compelling. There is now real hope and anticipation that novel ET receptor antagonists may eventually be used therapeutically against asthma and other major lung pathologies. It is this atmosphere of excitement created by new discoveries and the increasing scientific ratio nale for a significant impact ofthe ETs in pulmonary diseases that prompt ed the creation of this book, the first on this topic. Most of the information presented relates to ET-l, which is the most widely studied member of the ET family.


Pulmonary Actions of the Endothelins
Language: en
Pages: 292
Authors: Goldie
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer

GET EBOOK

The biology of the family of endogenous autocrine peptides known as the endothelins (ETs) has been a source of intense study for researchers since 1988, followi
The Pulmonary Endothelium
Language: en
Pages: 532
Authors: Norbert Voelkel
Categories: Medical
Type: BOOK - Published: 2009-08-25 - Publisher: John Wiley & Sons

GET EBOOK

The Pulmonary Endothelium is a uniquely comprehensive compendium of our current knowledge of the pulmonary endothelium and is the first book dedicated specifica
The Endothelium
Language: en
Pages: 309
Authors: Michel Félétou
Categories: Science
Type: BOOK - Published: 2011 - Publisher: Morgan & Claypool Publishers

GET EBOOK

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphati
Lung Endothelium
Language: en
Pages: 68
Authors: Mary I. Townsley
Categories: Medical
Type: BOOK - Published: 2015-09-01 - Publisher: Biota Publishing

GET EBOOK

Pulmonary endothelium forms the inner lining of blood vessels, where it interprets the complex mechanical and chemical environment within the circulation and ad
Drug-Induced Liver Disease
Language: en
Pages: 790
Authors: Neil Kaplowitz
Categories: Medical
Type: BOOK - Published: 2002-10-16 - Publisher: CRC Press

GET EBOOK

Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, inter