The Extracellular Matrix And The Tumor Microenvironment
Download The Extracellular Matrix And The Tumor Microenvironment full books in PDF, epub, and Kindle. Read online free The Extracellular Matrix And The Tumor Microenvironment ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
The Extracellular Matrix and the Tumor Microenvironment
Author | : Ilona Kovalszky |
Publisher | : Springer Nature |
Total Pages | : 493 |
Release | : 2022-07-06 |
Genre | : Medical |
ISBN | : 3030997081 |
Download The Extracellular Matrix and the Tumor Microenvironment Book in PDF, Epub and Kindle
This book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression. Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression. Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics. The series "Biology of Extracellular Matrix" is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
The Extracellular Matrix and the Tumor Microenvironment Related Books
Pages: 493
Pages: 189
Pages: 178
Pages: 121
Pages: 316