Metal-Based Neurodegeneration

Metal-Based Neurodegeneration
Author: Robert Crichton
Publisher: John Wiley & Sons
Total Pages: 628
Release: 2013-09-04
Genre: Medical
ISBN: 1118553519

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Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scientific findings, including details of their biochemical actors (proteins or peptides), their normal and pathological conformations, and a description of the diseases characteristics, with an emphasis on the role of metal-induced oxidative stress, which can result in the production of intracellular aggregates of target proteins and peptides. Topics covered include: Brain function, physiology and the blood-brain barrier Immune system and neuroinflammation Aging and mild cognitive impairment, MCI Parkinson’s Disease Alzheimer’s Disease Creutzfelt-Jakob and related prion diseases Alcoholic Brain Damage Therapeutic strategies to combat the onset and progression of neurological diseases This extensively updated, full colour, second edition of Metal-based Neurodegeneration is an essential text for research scientists and clinicians working in gerontology, neuropathology, neurochemistry, and metalloprotein mechanisms.


Metal-Based Neurodegeneration
Language: en
Pages: 628
Authors: Robert Crichton
Categories: Medical
Type: BOOK - Published: 2013-09-04 - Publisher: John Wiley & Sons

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Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiat
Metal-based Neurodegeneration
Language: en
Pages: 248
Authors: Robert Crichton
Categories: Medical
Type: BOOK - Published: 2006 - Publisher: Wiley

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This exciting new book opens a window into the causes of debilitating neurological disorders such as Parkinson’s disease, CJD and Huntington’s disease, and
Metal Ions and Neurodegenerative Disorders
Language: en
Pages: 538
Authors: Paolo Zatta
Categories: Medical
Type: BOOK - Published: 2003 - Publisher: World Scientific

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Numerous studies have established a clear connection between neuronal oxidative stress and several neurodegenerative diseases, with consequential damages to lip
Metals and Neurodegeneration: Restoring the Balance
Language: en
Pages: 134
Authors: Anthony R. White
Categories: Neurosciences. Biological psychiatry. Neuropsychiatry
Type: BOOK - Published: 2016-02-02 - Publisher: Frontiers Media SA

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Biometals such as copper, zinc and iron have key biological functions, however, aberrant metabolism can lead to detrimental effects on cell function and surviva
Metal Ions And Neurodengenerative Disorders
Language: en
Pages: 538
Authors: Paolo Zatta
Categories: Medical
Type: BOOK - Published: 2003-11-03 - Publisher: World Scientific

GET EBOOK

Numerous studies have established a clear connection between neuronal oxidative stress and several neurodegenerative diseases, with consequential damages to lip