Myeloid Cells In Health And Liver Disease
Download Myeloid Cells In Health And Liver Disease full books in PDF, epub, and Kindle. Read online free Myeloid Cells In Health And Liver Disease ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Myeloid cells in health and liver disease
Author | : Evangelos Triantafyllou |
Publisher | : Frontiers Media SA |
Total Pages | : 153 |
Release | : 2024-06-26 |
Genre | : Medical |
ISBN | : 2832550460 |
Download Myeloid cells in health and liver disease Book in PDF, Epub and Kindle
Cells of the myeloid lineage display diverse roles and functions both in tissue homeostatic conditions and during the development of liver diseases. Hepatic myeloid cells such asKupffer cells exert immune surveillance while maintaining immune tolerance. This helps to prevent excessive immune stimulation upon encounter with gut-derived antigens from food and commensal microbes, or rapidly identifying and eliminating pathogens. Myeloid cells also exhibit a dual role by contributing to both the initiation and progression of liver diseases. During liver inflammation, myeloid cells secrete cytokines and chemokines that promote chemotaxis and tissue damage. Further down the process they can undergo reprogramming into pro-resolving, anti-inflammatory cells. In extremis, these can lead to loss of liver function and development of fibrosis and cirrhosis. Liver myeloid cells can also dictate the progress of hepatic malignancy by either promoting the infiltration and activation or suppressing the activities of effector and/or cytotoxic T cells.
Myeloid cells in health and liver disease Related Books
Pages: 153
Pages: 892
Pages: 482
Pages: 335
Pages: 225