New Developments In The Pathogenesis Of Rheumatoid Arthritis
Download New Developments In The Pathogenesis Of Rheumatoid Arthritis full books in PDF, epub, and Kindle. Read online free New Developments In The Pathogenesis Of Rheumatoid Arthritis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
New Developments in the Pathogenesis of Rheumatoid Arthritis
Author | : Lazaros Sakkas |
Publisher | : BoD – Books on Demand |
Total Pages | : 166 |
Release | : 2017-02-22 |
Genre | : Medical |
ISBN | : 9535129694 |
Download New Developments in the Pathogenesis of Rheumatoid Arthritis Book in PDF, Epub and Kindle
The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-6, and also T cells and B cells, reinforced the pathogenetic role of the respective factors. ACPAs, induced by cigarette smoking and periodontitis in individuals with HLA-DRB1 shared epitope, appear to be autoantigens that initiate the inflammatory immune response in RA. MicroRNAs, part of epigenetic mechanisms, which also include DNA methylation, and histone modification, as well as microbiota, the composition of microbes in body cavities, also appear to influence arthritis and are discussed in this book.
New Developments in the Pathogenesis of Rheumatoid Arthritis Related Books
Pages: 166
Pages:
Pages: 6453
Pages: 462
Pages: 233