Nk Cell Subsets In Health And Disease New Developments
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NK Cell Subsets in Health and Disease: New Developments
Author | : Emanuela Marcenaro |
Publisher | : Frontiers Media SA |
Total Pages | : 245 |
Release | : 2017-11-29 |
Genre | : |
ISBN | : 2889453502 |
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Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.