Parp As A Therapeutic Target
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PARP as a Therapeutic Target
| Author | : Jei Zhang |
| Publisher | : CRC Press |
| Total Pages | : 363 |
| Release | : 2002-03-06 |
| Genre | : Medical |
| ISBN | : 1420042408 |
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Recent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the details of how PARP1 functions are still being elucidated, it has tremendous potential as a promising drug target. PARP inhibitors' dual actions of preventing cell death and abating inflammati
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Language: en
Pages: 363
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Type: BOOK - Published: 2002-03-06 - Publisher: CRC Press
Recent research in cell death mechanisms has rekindled interest in PARP's (Poly (ADP-Ribose) Polymerase) intriguing role in necrosis and apoptosis. While the de
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Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability t
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This is the most comprehensive, up-to-date reference on this post-translational modification of proteins, which is intimately linked with DNA repair, maintenanc
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One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriat
